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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6
All Species:
11.82
Human Site:
S1380
Identified Species:
21.67
UniProt:
Q03468
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03468
NP_000115.1
1493
168416
S1380
R
A
E
D
A
D
S
S
S
G
P
L
A
S
S
Chimpanzee
Pan troglodytes
XP_507781
1491
168031
S1378
R
A
E
D
A
D
S
S
S
G
A
L
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001107536
1496
168876
S1383
R
A
E
D
A
D
S
S
S
G
A
L
A
S
S
Dog
Lupus familis
XP_534944
1486
168108
S1373
K
V
E
D
A
E
S
S
P
G
A
L
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001100766
1325
148468
K1221
S
G
A
P
A
G
V
K
M
R
A
R
N
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508174
968
109820
V864
G
T
R
V
P
H
L
V
K
Q
K
R
Y
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24368
1027
118855
N923
K
L
G
F
D
K
E
N
V
Y
E
E
L
R
A
Honey Bee
Apis mellifera
XP_001120586
932
107557
H828
K
S
S
I
S
E
N
H
T
T
S
A
L
F
E
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
E905
N
K
G
K
T
Y
T
E
E
E
D
R
F
L
V
Sea Urchin
Strong. purpuratus
XP_001193315
953
107227
L849
M
P
S
S
N
S
L
L
N
R
M
R
A
R
N
Poplar Tree
Populus trichocarpa
XP_002307656
1206
134941
E1101
A
R
I
R
G
N
Q
E
R
A
V
G
A
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWY3
1057
122611
D953
K
L
Y
N
E
E
C
D
R
F
M
I
C
M
I
Baker's Yeast
Sacchar. cerevisiae
P40352
1085
124509
L981
L
T
G
S
A
A
I
L
G
N
I
T
K
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.3
N.A.
N.A.
70.1
N.A.
44.6
N.A.
N.A.
N.A.
N.A.
20
31.4
20.6
36.4
Protein Similarity:
100
99.4
97.9
89.1
N.A.
N.A.
76.4
N.A.
52.2
N.A.
N.A.
N.A.
N.A.
35.7
43.8
35.7
45.8
P-Site Identity:
100
93.3
93.3
60
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
0
0
6.6
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
40
6.6
20
Percent
Protein Identity:
29.4
N.A.
N.A.
23.5
28.4
N.A.
Protein Similarity:
44.9
N.A.
N.A.
38.2
43.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
8
0
47
8
0
0
0
8
31
8
39
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
31
8
24
0
8
0
0
8
0
0
0
0
% D
% Glu:
0
0
31
0
8
24
8
16
8
8
8
8
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
8
8
0
% F
% Gly:
8
8
24
0
8
8
0
0
8
31
0
8
0
8
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
8
0
0
8
0
0
0
8
8
0
0
8
% I
% Lys:
31
8
0
8
0
8
0
8
8
0
8
0
8
0
8
% K
% Leu:
8
16
0
0
0
0
16
16
0
0
0
31
16
8
8
% L
% Met:
8
0
0
0
0
0
0
0
8
0
16
0
0
8
8
% M
% Asn:
8
0
0
8
8
8
8
8
8
8
0
0
8
0
8
% N
% Pro:
0
8
0
8
8
0
0
0
8
0
8
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
8
% Q
% Arg:
24
8
8
8
0
0
0
0
16
16
0
31
0
24
0
% R
% Ser:
8
8
16
16
8
8
31
31
24
0
8
0
0
39
31
% S
% Thr:
0
16
0
0
8
0
8
0
8
8
0
8
0
0
0
% T
% Val:
0
8
0
8
0
0
8
8
8
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _